Of the 18 CTL clones studied, 1 recognizes NP and the other 17 recognize GP.
The second is recognized by all 12 of the remaining clones and was mapped, by using the GP deletions, to a 22-amino-acid region comprising GP residues 272 to 293. A synthetic peptide representing this area sensitized uninfected syngeneic target cells to lysis both by bulk CTL obtained from the spleen after a primary immunization and by appropriate CTL clones. Two sets of criteria are available which are said to identify potential T-cell epitopes, one based on primary amino acid sequence and the second based on protein secondary structure. Neither of these predictive schemes would have identified region 272 to 293 as a CTL recognition motif, indicating that such programs are of limited usefulness as presently conceived.
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At the outset of World War I, the popularity of the colonial troops at the time led to the replacement of the West Indian by the now more familiar jolly Senegalese infantry man enjoying Banania. Her image was replaced in 1915 with the drawing of a widely smiling Senegalese man. When he returned to Paris, he started its commercial fabrication and, in 1912, began marketing Banania with the picture of an Antillaise.
The form of the character has since evolved to more of a cartoon character. The slogan Y'a bon ("It's good") derives from the pidgin French supposedly used by these soldiers (it is, in fact, an invention). The brand's yellow background underlines the banana ingredient, and the Senagalese infantryman's red and blue uniform make up the other two main colours.
In France the Banania brand is now owned by the newly founded French company Nutrial, which acquired it from Unilever in 2003. In the 1970s and early 1980s, Banania sponsored the Yellow Jersey of the Tour de France. Posters and reproduction tin-plate signs of the pre-war advertising continue to be sold.
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